Deadly shooting in Mount Vernon.

From 8 to 9:30 a.m., families can head out to the event to receive clear backpacks, school supplies and jeans at no cost.

SIKESTON, Mo. (KFVS) - A man and a juvenile were arrested in connection with a shots-fired investigation in Sikeston. James A. Taylor, Jr., 21, of Cairo, Illinois, was charged in New Madrid County ...

Aaron Muse, 34 ...

SIKESTON, Mo. (KFVS) - A woman is wanted in two counties on charges of burglary and tampering with vehicles. Aaron Muse, 34, ...

Police in Carbondale need the community’s help as they search for a suspect wanted in connection with a burglary ...

The Murphysboro Emergency Management Agency is letting the public know the annual signal maintenance is happening this week.

CAPE GIRARDEAU, Mo. (KFVS) - Saint Francis Healthcare System will celebrate 150 years of service in southeast Missouri. And to mark the occasion, a ribbon-cutting ceremony will take place in front of ...

Colorado coach Deion Sanders disclosed Monday that he was diagnosed with an aggressive form of bladder cancer but after surgery his oncologist considered him cured.

One person is in custody in connection with a shooting in Caruthersville, Mo.

A Mississippi man pleaded guilty and was sentenced for a deadly shooting in 2021 at a Jackson, Mo. motel.

BG's Deli in Cape Girardeau, Mo. announced it will close at the end of August.