Andre Onana sustained a hamstring injury in July and had to sit out the preseason friendly matches. The Cameroonian goalkeeper is reportedly ready return to action in the Red Devils' opening Premier League match.

Elsewhere, Man United will be without Noussair Mazraoui due to injury. The versatile defender joins long-term absentee Lisandro Martinez as the two players guaranteed to miss out against Arsenal. Andre Onana and Joshua Zirkzee missed the entirety of pre-season, but have since returned to full training and are options to the matchday squad.

Kickoff from Old Trafford in Manchester is set for 11:30 a.m. ET. The Gunners are -118 favorites (risk $118 to win $100) on the 90-minute money line in the latest Manchester United vs. Arsenal odds, while Man United are +310 underdogs.