Benralizumab is an eosinophil-depleting anti–interleukin-5 receptor α monoclonal antibody. The efficacy and safety of benralizumab in patients with eosinophilic esophagitis are unclear.In a ...

Benralizumab is a humanized, afucosylated monoclonal antibody with high affinity and specificity for the human interleukin-5 receptor α subunit (interleukin-5Rα) expressed on eosinophils 14 and ...

Among 211 patients ages 12 to 65 years, 87.4% of those receiving benralizumab had a histologic response -- defined as at least six eosinophils per high-power field -- compared with 6.5% of ...

Benralizumab is noninferior to mepolizumab in achieving remission of relapsing or refractory eosinophilic granulomatosis with polyangiitis at 36 and 48 weeks, according to data published in The ...

Benralizumab, an anti–interleukin-5 receptor alpha monoclonal antibody, was significantly better than placebo at producing a histologic response of up to six eosinophils per high-power field ...

Mepolizumab and benralizumab had similar safety profiles for patients with severe eosinophilic asthma despite their different mechanisms, according to a study published in The Journal of Allergy ...

Treating eosinophilic exacerbations of asthma and COPD with benralizumab (ABRA): a double-blind, double-dummy, active placebo-controlled randomised trial, The Lancet Respiratory Medicine.

The benralizumab group not only had fewer symptoms, but it also took longer for them to suffer an event so severe they had to either see a doctor or go to the hospital, researchers found.

Diagrammatic illustration of the mechanism of two monoclonal antibodies utilized for treating eosinophilic asthma, mepolizumab, and benralizumab. Mepolizumab specifically targets interleukin-5 (IL ...

Benralizumab, sold as Fasenra, is an anti-IL-5 receptor alpha monoclonal antibody that induces rapid, direct, almost complete depletion of eosinophils.

Gastroenterology > General Gastroenterology Benralizumab Led to Histologic Responses in Eosinophilic Esophagitis — But there was no significant difference in symptom relief compared with placebo ...