The First Four produced a thrilling finish in its opening game with Alabama State beating St. Francis 70-68 on a layup with a second left. That was followed with a dud when North Carolina, the tournament's most controversial team, absolutely blasted San Diego State to make the round of 64.

Women’s NCAA Division I tournament begins on Wednesday, March 19, 2025 (3/19/25) with a pair of First Four contests.

Now, eight teams will go head-to-head to secure the final vacant spots in the 2025 NCAA Tournament bracket. On Tuesday and Wednesday, March Madness will officially begin with the First Four matchups.