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A promising strategy to reduce the impact of viral infectious diseases, such as influenza, is the use of attenuated, live viruses as vaccines. However, the usefulness of traditional ...
In the 2007-2008 flu season, the inactivated vaccine was more effective than the live attenuated vaccine in preventing laboratory-confirmed symptomatic influenza A (mostly H3N2) in healthy ...
“Delivery of the vaccine to the respiratory tract provides upfront, initial immune response,” Gauger said. Gauger said the live attenuated influenza virus vaccines may also provide better ...
Influenza vaccines reduced the risk of influenza illness overall during the 2015-2016 season, according to data published in the New England Journal of Medicine. However, the live attenuated ...
Prior to the nasal administration of the live-attenuated flu vaccine candidate called NS1 (1-126)-ΔPAX, the animals were primed with a vesicular stomatitis virus (VSV) as a vaccine delivery ...
All the influenza vaccines (inactivated, recombinant and live attenuated) available in the United States during the 2021-22 flu season are quadrivalent. That means they contain four ...
“The nasal spray flu vaccine is licensed for use in otherwise healthy, non-pregnant people ages 2 through 49 years,” he said. FluMist is a live attenuated influenza vaccine.
However, the usefulness of traditional live-attenuated virus vaccines has often been limited by suboptimal immunogenicity, safety concerns, or cumbersome manufacturing processes and techniques.
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